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. 2022 May 16;5:467. doi: 10.1038/s42003-022-03405-w

Fig. 2. Glucose metabolism and tolerance is improved in TrxR2-Tg mice maintained on standard chow and high-fat diet.

Fig. 2

a TrxR2-Tg mice have lower basal blood glucose, 7 months old mice (ANOVA with Tukey’s test, n = 7–9). b Chow-fed 8-month-old TrxR2-TG mice show improved glucose tolerance compared to littermate controls (n = 7–9) separate tests were done for female and male groups. c Chow-fed 8-month-old TrxR2-TG mice have higher insulin sensitivity than littermate controls separate tests were done for female and male groups (n = 8–9). d Schematic of high-fat diet feeding regime used in panels e, f. e High-fat diet-fed 8 months old TrxR2-Tg mice show improved glucose tolerance compared to littermate controls separate tests were done for female and male groups (n = 8–10). f High-fat diet-fed 8 months old, males and females TrxR2-Tg mice have decreased liver fat compared to littermate controls. Oil Red O stain of liver slices, n = 8. Values are Mean ± SEM. *p < 0.05, **p < 0.01.