Table 5.
The Comparison of Severe Adverse Events (≥Grade III) of 173 mCRC Patients Between the Cetuximab Group and Bevacizumab Group
| Cetuximab (N = 98) | Bevacizumab (N = 75) | p Value | |
|---|---|---|---|
| Events | 25 (25.5%) | 20 (26.7%) | 0.658 |
| Neutropenia | 7 (7.1%) | 6 (8.0%) | |
| Anemia | 4 (4.1%) | 6 (8.0%) | |
| Oral mucositis | 2 (2.0%) | 1 (1.3%) | |
| Diarrhea | 0 (0.0%) | 2 (2.6%) | |
| Paresthesia | 3 (3.1%) | 0 (0.0%) | |
| Nausea/vomiting | 4 (4.1%) | 3 (4.0%) | |
| Liver function impairment | 1 (1.0%) | 2 (2.6%) | |
| Renal function impairment | 3 (3.1%) | 0 (0.0%) | |
| Alopecia | 1 (1.0%) | 0 (0.0%) |
All mCRC patients with wild-type RAS gene.