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. 2022 May 16;12:8064. doi: 10.1038/s41598-022-12147-y

Table 8.

Comparison of the performance of our proposed model with previous studies of glaucoma detection combining structural and functional features.

Studies Method Trained features AUC Accuracy (%) Sensitivity (%) Specificity (%) No. of patients
Kim et al.22 RF model Age, IOP, CCT, Average RNFL thickness, GHT, MD and PSD 0.98 98 98.3 97.5 202 healthy and 297 glaucoma
Brigatti et al.23 NN (Back propagation) MD, corrected loss, variance, short term, fluctuation, CDR, rim area, cup volume, and RNFL height 88 90 84 54 healthy and 185 glaucoma
Bowd et al.24 RVM OCT RNFL thickness measurements, MD, and PSD 0.85 81 72 69 healthy and 156 glaucoma
Grewal et al.25 ANN RNFL parameters on OCT, cup area, vertical CDR, cup volume, MD, loss variance, and GDx- Variable Corneal Compensation (VCC) parameters 93.3 80 35 healthy and 35 glaucoma
Eliash et al.51 SVM Horizontal integrated rim width (HIRW), rim area, HCDR, vertical CDR, Mean NFL, NFL inferior, NFL superior, NFL 6, NFL 7, NFL 11, and MD 0.98 96.6 97.9 92.5 47 healthy and 42 glaucoma
Proposed study DL MD, PSD, Average RNFL thickness and CDR 0.98 97% (validation data), 96% (test data) 100% (validation and test data) 96% (validation data), 93% (test data) 130 healthy and 125 glaucoma