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. 2022 May 16;5:470. doi: 10.1038/s42003-022-03414-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Representative immunofluorescence images of OCT4 in the hiPSCs (n = 3). b Representative immunofluorescence images of α-actinin and cTnT in the hiPSC-CMs (n = 6). c Representative images and quantification of the velocity of contraction and relaxation of hiPSC-CMs. d–g Representative immunoblotting images and quantification of the expression of p-AKT, NRF2, MFN2, FAS, and TECRL in hiPSC-CMs following TECRL knockdown. Values are mean ± SE. P < 0.05 was considered significant.