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. 2022 May 3;13:872542. doi: 10.3389/fimmu.2022.872542

Table 4.

Comparison of the results of random-effects vs. fixed-effects models.

Analysis groups HR (95% CI), random-effects model HR (95% CI), fixed-effects model
Total 0.65 (0.60, 0.71) 0.74 (0.73, 0.76)
Influenza vaccination 0.74 (0.63, 0.87) 0.89 (0.87, 0.91)
Herpes zoster vaccination 0.69 (0.66, 0.73) 0.69 (0.67, 0.72)
Tdap vaccination 0.69 (0.58, 0.82) 0.80 (0.77, 0.84)
BCG vaccination 0.42 (0.17, 1.07) 0.62 (0.50, 0.76)
Pneumonia vaccination 0.68 (0.41, 1.13) 1.00 (0.96, 1.03)
Poliomyelitis vaccination 0.78 (0.44, 1.40) 0.95 (0.80, 1.11)
Other vaccination 0.77 (0.73, 0.81) 0.78 (0.74, 0.81)
Male 0.66 (0.58, 0.74) 0.65 (0.60, 0.69)
Female 0.67 (0.63, 0.72) 0.67 (0.63, 0.72)
<70 years 0.74 (0.66, 0.84) 0.74 (0.70, 0.78)
≥70 years 0.64 (0.57, 0.72) 0.72 (0.71, 0.74)
1 dose vaccine 1.03 (0.98, 1.08) 1.03 (0.98, 1.08)
2-3 dose vaccine 0.87 (0.74, 1.02) 0.94 (0.91, 0.98)
≥4 dose vaccine 0.51 (0.32, 0.80) 0.65 (0.62, 0.68)
Alzheimer’s disease 0.63 (0.55, 0.72) 0.78 (0.75, 0.81)