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. 2022 May 3;12:853768. doi: 10.3389/fonc.2022.853768

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Copyright © 2022 Yu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A comparison of the landscape topography variations fir IGC with Helicobacter pylori infection. The X and Y-axes represent the gene expression levels of hTERT and MYC, respectively, while the Z-axis represents the variations in H. H denotes the degree of Helicobacter pylori infection. N, AG, IM, and C represent the normal, atrophic gastritis, intestinal metaplasia, and gastric cancer states, respectively. (A) is the comparison of the 2-dimensional landscape. (B) is the comparision of the 3-dimensional landscape.