Skip to main content
. 2022 Apr 7;9(17):2105904. doi: 10.1002/advs.202105904

Table 2.

Examples of commercial POCT platforms that are available to market for virus detection

Detection Production Target Method Amplification Sensitivity a) Time to result [min] d) Manufacturer Website
HIV‐1 m‐PIMA HIV‐1/2 VL HIV‐1 group M, group N and group O, HIV‐2 Microfluidic chips Real‐time qRT‐PCR 800 copies mL−1 <70 min Abbott www.abbott.com
HIV‐1 Xpert HIV‐1 VL HIV‐1 group M, group N and group O Microfluidic chips Real‐time qRT‐PCR 40–107 copies mL−1 <90 min Cepheid www.cepheid.com
HIV‐1/HIV‐2/HCV/HBV Cobas TaqScreen MPX Test N/A Nucleic acid amplification Multiple real‐time PCR 50 copies mL−1 (HIV), b) 50 copies mL−1 (HCV), 10 copies mL−1 (HBV) c) <60 min Roche www.roche.com
HIV‐1/HCV/HBV Ultrio N/A Nucleic acid amplification Multiple real‐time PCR 44.6 IU mL−1 (HIV), 10.44 IU mL−1 (HBV),3.01 IU mL−1 (HCV) <60 min Novartis www.novartis.com
HIV‐1/HIV‐2 Alere q HIV‐1/2 HIV‐1 group M, group N and group O, HIV‐2 Nucleic acid amplification Real‐time PCR 2937 IU mL−1 <60 min Abbott www.abbott.com
Influenza A/B Cobas Liat Influenza A/B N/A Microfluidic chips Real‐time PCR 10−2–10−1 TCID50 mL−1 (Influenza A)/10−3–10−1 TCID50 mL−1 (Influenza B) 15–20 min Roche www.diagnostics.roche.com
Influenza A/B ID NOW INFLUENZA A & B 2 N/A Microfluidic chips Isothermal (RPA) N/A <13 min Abbott www.abbott.com
Influenza A/B BD veritor system Flu A+B N/A Immunochromatographic strip N/A N/A 15–20 min BD www.bd.com
Ebola virus Film array NCDS BT‐E N/A FilmArray NGDS BTE assay pouches Real‐time qRT‐PCR 100 PFU mL−1 1 h BioFire www.biofireinc.com
Ebola virus Lightcycler,COBAS Z480 N/A High pure viral nuclenic acid Kit Real‐time qRT‐PCR 4781 PFU mL−1 3 h Roche www.roche.com
Ebola virus LA‐200 Nucleoprotein coding genes Nucleic acid amplification Isothermal (LAMP) 104–105 copies mL−1 <60 min Eiken www.eiken.co.jp
HIV LIAISON 200 tests 310260 XL murex HIV Ab/Ag p24 antigen Chemiluminescence immunoassay N/A 27.4 pg mL−1 <60 min Diasorin www.diasorin.com
HIV‐1/HIV‐2 HIV(I+2) rapid test strip N/A Rapid test strip N/A N/A <15 min Kehua Bio‐engineering www.skhb.com
Syphilis Rapid test strip Syphilis antigen Rapid test strip N/A N/A 15–20 min Wondfo www.wondfo.com.cn
Ebola virus ReEBOV antigen rapid test Antigen VP40 Rapid test strip N/A 1.0 × 106 PFU mL−1 <15 min Corgenix www.corgenix.com
Ebola virus OraQuick Ebola rapid antigen test Antigen Rapid test strip N/A 1.64 × 106 PFU mL−1 30 min OraSure www.oraSure.com
a)

International unit: IU (WHO International Standard Unit); Plaque‐forming units: PFU; Tissue culture infective dose: TCID;

b)

diagnostic sensitivity at limit of detection with WHO 3rd International Standard, 1000 copies mL−1;

c)

1 IU mL‐−1 ∼  5.6 copies mL−1, which is defined by the WHO;

d)

time to result depends upon the particular assay.