TABLE 1.
Comparison of epidemiological data and baseline laboratory tests between survivor and nonsurvivor patients with COVID‐19
| Variable | Overall | Survivors | Nonsurvivors | p value |
|---|---|---|---|---|
| n = 359 | n = 174 | n = 185 | ||
| Characteristics | ||||
| Age in years, mean (SD) | 54.3 (14.69) | 50 (14.31) | 58.4 (13.88) | <0.001 a |
| SBP, mm Hg | 124.71 (26.71) | 122.73 (15.62) | 126.58 (33.39) | 0.1 |
| DBP, mm Hg | 73.21 (12‐9) | 74.46 (11.09) | 72.04 (14.33) | 0.07 |
| Sex (male) n (%) | 257 (71.59) | 123 (47.86) | 134 (52.14) | 0.7 b |
| Intubation | 141 (39.28) | 18 (12.77) | 123 (87.23) | <0.001 |
| Symptoms | ||||
| Fever, n (%) | 247 (68.8) | 122 (49.39) | 125 (50.61) | 0.6 b |
| Dyspnea | 233 (64.9) | 112 (64.37) | 121 (65.41) | 0.9 |
| Cough | 210 (58.5) | 103 (59.2) | 71 (40.8) | 0.8 |
| Myalgia | 151 (42.06) | 75 (43.1) | 76 (41.08) | 0.7 |
| Arthralgia | 146 (40.67) | 72 (41.38) | 74 (70) | 0.8 |
| Headache | 75 (20.89) | 39 (22.41) | 36 (19.46) | 0.5 |
| Pharyngalgia | 53 (14.76) | 30 (56.6) | 23 (43.4) | 0.2 |
| Chest pain | 36 (10.03) | 18 (10.34) | 18 (9.73) | 0.8 |
| Diarrhea | 23 (6.41) | 12 (6.9) | 11 (5.95) | 0.8 |
| Vomiting | 14 (3.9) | 10 (5.75) | 4 (2.16) | 0.1 |
| Anosmia | 6 (1.61) | 4 (2.3) | 2 (1.08) | 0.4 |
| Comorbilities | ||||
| Overweight n (%) | 120 (33.43) | 59 (33.91) | 61 (32.97) | 0.9 b |
| Hypertension | 55 (15.32) | 17 (9.77) | 38 (20.54) | 0.005 |
| Type 2 diabetes | 52 (14.48) | 21 (12.07) | 32 (17.3) | 0.1 |
| Obesity | 36 (10.03) | 11 (6.32) | 25 (13.51) | 0.03 |
| COPD | 11 (3.06) | 7 (4.02) | 4 (2.16) | 0.2 |
| Laboratory tests | ||||
| Hemoglobin in g/dL, mean (SD) | 14.36 (3.67) | 14.6 (4.32) | 14.1 (2.92) | 0.2a |
| Platelets, 103 | 238.97 (114.43) | 233.95 (110.6) | 243.7(118.01) | 0.4 |
| Leukocytes, 103/µL | 9.55 (4.8) | 7.95 (3.82) | 11.05 (5.14) | <0.001 |
| Lymphocytes, 103/µL | 1.12 (0.79) | 1.17 (0.81) | 1.06 (0.77) | 0.2 |
| Neutrophils, 103/µL | 8.34 (6.5) | 6.5 (3.9) | 9.99 (7.86) | <0.001 |
| Creatinine, mg/dL | 1.97 (6.58) | 2.21 (9.18) | 1.75 (2.22) | 0.5 |
| Glucose, mg/dL | 153.51 (101.01) | 130.6 (86.92) | 175.05 (108.43) | <0.001 |
| Urea, mg/dL | 55.18 (48.21) | 43.66 (45.04) | 65.96 (48.69) | <0.001 |
| ALT, UI/L | 55.23 (86.7) | 47.68 (33.08) | 62.32 (116.16) | 0.1 |
| AST, UI/L | 79.14 (368.8) | 48.11(28.79) | 108.32 (511.97) | 0.1 |
| Albumin, g/dL | 3.32 (1.79) | 3.67 (2.45) | 3 (0.65) | <0.001 |
| TB, mg/dL | 0.98 (3.97) | 0.67 (0.4) | 1.28 (5.48) | 0.1 |
| HDL‐C, mg/dL | 27.19 (15.77) | 32.13 (19.32) | 22.55 (9.39) | <0.001 |
| Triglycerides, mg/dL | 273.3 (214.78) | 216.75 (150.1) | 326.49 (250.4) | <0.001 |
| CRP, mg/dL | 156.96 (127.82) | 120.89 (108.24) | 188.93(135.39) | <0.001 |
| LDH, UI/L | 708.89 (696.1) | 560.09 (348.02) | 840.33 (878.08) | <0.001 |
| FIB‐4 score | 3.14 (7.54) | 2.12 (3.51) | 4.1 (9.86) | 0.01 |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; COPD, chronic obstructive pulmonary disease; COVID‐19, coronavirus disease 2019; CRP, C‐reactive protein; DBP, diastolic blood pressure; FIB‐4, fibrosis‐4; HDL‐C, high‐density lipoprotein cholesterol; LDH, lactate dehydrogenase; SBP, systolic blood pressure; TB, total bilirubin.
a
Two‐tailed t test for independent measures.
b
Fisher´s exact test.