Table 2.
The impacts of MCE on clinical outcome.
| MCE | No./No. (%) | P-value | OR (95%CI) | P | Adjusted OR (95%CI) | P | |
|---|---|---|---|---|---|---|---|
| 90-day mRS 0-3, n (%) | Non-MCE | 77 (36.67) | <0.001 c | 0.19 (0.10-0.36) | <0.001 | 0.35 (0.18,0.68) g | 0.002 |
| MCE | 12 (10.08) | ||||||
| mRS, median (IQR) | Non-MCE | 5 (2-6) | <0.001 d | 5.37 (3.35,8.82) e | <0.001 | 2.86 (1.69,4.92) h | <0.001 |
| MCE | 6 (5-6) | ||||||
| Mortality in hospital, n (%) | Non-MCE | 34 (16.19) | 0.005 c | 2.16 (1.26,3.71) | 0.005 | 1.19 (0.63,2.24) g | 0.588 |
| MCE | 35 (29.41) | ||||||
| Mortality at 90 d, n (%) | Non-MCE | 72 (34.29) | <0.001 c | 5.69 (3.47,9.51) | <0.001 | 3.24 (1.79,5.95) g | <0.001 |
| MCE | 89 (74.79) | ||||||
| ΔNIHSS at 24 h
a
, median (IQR) |
Non-MCE | -5.00 (-11.00, 2.00) | <0.001 d | 4.26 (2.17,6.35) f | <0.001 | 3.38 (1.31,5.44) i | 0.001 |
| MCE | 2.00 (0.00, 6.00) | ||||||
| ΔNIHSS at 5-7 d
b
, median (IQR) |
Non-MCE | 0.00 (-5.00 to 2.00) | <0.001 d | 7.29 (4.72,9.86) f | <0.001 | 5.96 (3.46,8.46) i | <0.001 |
| MCE | 2.00 (0.00 to 6.00) |
Change from NIHSS at admission from NIHSS at 24 h after EVT.
Change from NIHSS at admission from NIHSS at 5-7 days after EVT.
Chi-square test.
Wilcoxon test.
Common OR.
ß-values were estimated from a univariate linear regression model.
Adjusted OR; adjusted estimates of outcome were calculated using multiple regression, taking the following variables into account: baseline NIHSS score, baseline PC-ASPECTS, neutrophil count, mTICI, PC-CS score, occlusion sites, and onset to recanalization time.
Adjusted common OR; adjusted estimates of outcome were calculated using multiple regression, taking the following variables into account: baseline NIHSS score, baseline PC-ASPECTS, neutrophil count, mTICI, PC-CS score, occlusion sites, and onset to recanalization time.
ß-values were estimated from a multivariable linear regression model; adjusted estimates of outcome were calculated using multiple regression, taking the following variables into account: baseline NIHSS score, baseline PC-ASPECTS, neutrophil count, mTICI, PC-CS score, occlusion sites, and onset to recanalization time.
NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin Scale score at 90 days; MCE, malignant cerebellar edema; PC-CS, posterior circulation collateral system score; mTICI, modified thrombolysis in cerebral infarction; PC-ASPECTS, posterior circulation Alberta Stroke Program Early CT Score.