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. 2022 Apr 8;32(5):e2347. doi: 10.1002/rmv.2347

FIGURE 4.

FIGURE 4

Assignment of epitope residues of spike protein for binding to Angiotensin‐converting enzyme 2 (ACE2) and SARS‐CoV‐2 neutralising monoclonal antibodies (MAbs). Epitope residues of (a) Receptor binding domain (RBD), (b) N‐terminal domain (NTD), (c) Furin cleavage site, and (d) SH‐targeting neutralising MAbs are highlighted in different colours. ACE2: Angiotensin‐converting enzyme 2, SARS‐CoV‐2: Severe acute respiratory syndrome coronavirus 2; NTD: N‐terminal domain; RBD: Receptor binding domain; SH: Stem helix