FIGURE 1.

Schematic model of the SARS-CoV-2 whit its structural proteins. (A) The virus envelope is associated with four structural proteins: membrane protein (M); spike protein (S); envelope protein (E); and nucleocapsid protein (N). Moreover, it has a single-stranded positive sense RNA and a genome approximately 29.9 kb in size. (B) To enter a host cell, the SARS-CoV-2 spike protein interacts with the ACE2 and neuropilin-1, while TMPRSS2 to activate its membrane-fusion capacity and subsequent endocytosis.