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. 2022 Mar 8;166(1):68–77. doi: 10.1111/imm.13450

FIGURE 1.

FIGURE 1

Association between HLA DRB1 alleles, the presence of case definition symptoms and T cell immune responses to SARS‐CoV‐2 following natural infection: (a) consistent association of DRB1*13:02 with the presence of case definition symptoms; (b) Association between the absence of HLA‐DRB1*15:02 and T‐cell responses against nucleoprotein peptide pool (HLA‐DRB1*15:02 −, n = 68, HLA‐DRB1*15:02 +, n = 5). Bars show mean with SD. P value calculated using a Mann–Whitney U test. PBMC for T cell assays were taken on average 121 (range 71–174) days following first presentation of case definition symptoms. HLA, human leukocyte antigen; PBMC, peripheral blood mononuclear cells