TABLE 4.
Demographics of hospitalized COVID‐19 patients with and without AUD
|
No AUD or alcohol complication n = 196,257 a |
AUD or alcohol complication n = 6669 a |
p value 2 | |
|---|---|---|---|
| Age, median (IQR) | 60 (44, 72) | 57 (44, 66) | <0.001 |
| Age group | |||
| <29 | 16963 (8.6%) | 412 (6.2%) | <0.001 |
| 30 to 49 | 45618 (23%) | 1831 (27%) | |
| 50 to 64 | 54844 (28%) | 2572 (39%) | |
| ≥65 | 78832 (40%) | 1854 (28%) | |
| Male sex | 97510 (50%) | 4787 (72%) | <0.001 |
| Race/ethnicity | <0.001 | ||
| Non‐Hispanic white | 88789 (45%) | 3372 (51%) | |
| Black or African American | 41955 (21%) | 1537 (23%) | |
| Hispanic or Latino | 37648 (19%) | 1064 (16%) | |
| Other | 22123 (11%) | 596 (8.9%) | |
| Missing/unknown | 5742 (2.9%) | 100 (1.5%) | |
| Current or former smoker | 54983 (28%) | 2883 (43%) | <0.001 |
| BMI categories | <0.001 | ||
| Underweight (<18.5) | 5074 (2.6%) | 386 (5.8%) | |
| Normal weight (18.5 to 24.9) | 33031 (17%) | 1880 (28%) | |
| Overweight (25.0 to 29.9) | 50377 (26%) | 1848 (28%) | |
| Obese (≥30.0) | 89540 (46%) | 2327 (35%) | |
| Unknown/missing | 18235 (9.3%) | 228 (3.4%) | |
| Individual comorbidities | |||
| Hypertension | 71045 (36%) | 4383 (66%) | <0.001 |
| Diabetes mellitus | 43925 (22%) | 2281 (34%) | <0.001 |
| Myocardial infarction | 9858 (5.0%) | 777 (12%) | <0.001 |
| Congestive heart failure | 21165 (11%) | 1435 (22%) | <0.001 |
| Peripheral vascular disease | 17811 (9.1%) | 1240 (19%) | <0.001 |
| Stroke | 16024 (8.2%) | 1127 (17%) | <0.001 |
| Dementia | 6476 (3.3%) | 421 (6.3%) | <0.001 |
| Chronic pulmonary disease | 29264 (15%) | 2147 (32%) | <0.001 |
| Rheumatologic disease | 7496 (3.8%) | 347 (5.2%) | <0.001 |
| Peptic ulcer disease | 2635 (1.3%) | 427 (6.4%) | <0.001 |
| Cirrhosis | 2968 (1.5%) | 1448 (22%) | <0.001 |
| Hemiplegia or paraplegia | 2880 (1.5%) | 197 (3.0%) | <0.001 |
| Renal disease | 24650 (13%) | 1352 (20%) | <0.001 |
| Any malignancy (except skin) | 16931 (8.6%) | 846 (13%) | <0.001 |
| Metastatic solid tumor | 3828 (2.0%) | 210 (3.1%) | <0.001 |
| HIV/AIDS | 1188 (0.6%) | 160 (2.4%) | <0.001 |
| Multiple comorbidities | 97017 (49%) | 5633 (84%) | <0.001 |
| Outcomes | |||
| Acute kidney injury | 32630 (17%) | 1232 (18%) | <0.001 |
| Invasive mechanical ventilation | 18728 (9.5%) | 609 (9.1%) | 0.3 |
| Death or transfer to hospice | 23397 (12%) | 878 (13%) | 0.002 |
| Inpatient therapies | |||
| Steroids | 39220 (20%) | 1011 (15%) | <0.001 |
| Remdesivir | 5246 (2.7%) | 265 (4.0%) | <0.001 |
| Transfusion | 15062 (7.7%) | 497 (7.5%) | 0.5 |
| Vasopressor | 39220 (20%) | 1011 (15%) | <0.001 |
2
Wilcoxon rank sum test; Pearson's Chi‐squared test.
a
Median (IQR); n (%).