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. 2022 Apr 3;24(7):1385–1389. doi: 10.1111/dom.14692

TABLE 2.

Multivariate analysis of clinical factors independently associated with the death in patients hospitalized due to COVID‐19

Variable Death within 30 days
Logit coefficient SE OR SE
Wave 1 0.372 0.305 1.451 0.416
Age 0.0601 ** 0.00802 1.062 ** 0.00825
Weight (kg) −0.000987 0.00463 0.999 0.00451
Female −0.325 0.167 0.723 0.124
White 0.104 0.169 1.11 0.19
Diabetes −0.0793 0.231 0.924 0.191
Stroke 0.00737 0.223 1.007 0.2
Heart disease (IHD +/− CCF) 0.486 ** 0.185 1.625 ** 0.284
Hypertension 0.149 0.179 1.161 0.213
Admission eGFR −0.0176 ** 0.00326 0.983 ** 0.00316
FiO 2 (maximum during admission) 0.0329 ** 0.0107 1.033 ** 0.0115
Dexamethasone usage—patients without diabetes −0.184 0.378 0.832 0.311
Dexamethasone usage—patients with diabetes 0.0323 0.419 1.033 0.405
Remdesivir −0.397 0.254 0.673 0.164
Tociluzimab −1.22 * 0.609 0.295 * 0.173
Residual FiO2 0.0147 0.0113
Constant −6.46** 0.932

Note: Unselected multivariate logistic (Logit) analysis of clinical variables that were collected for patients admitted with swab positive COVID‐19 in Wave 1 and Wave 2 combined, as applied to the outcome of death within 30 days. Regressors were included if accurate data was available for >80% of the combined pool of 2261 patients. For categorical variables, a positive “estimate” indicates an increased risk of the outcome (death) with that variable present, and a negative estimate indicates a reduced risk of the outcome (death) if that variable is present. For continuous variables, a positive “estimate” indicates an increased risk of the outcome (death) with that variable increasing, and a negative estimate indicates a reduced risk of the outcome (death) if that variable is decreasing. The P value is a measure of the confidence of that variable being an independent predictor of the primary outcome corrected for all of the other regressors listed. Bold values are used to highlight variables with significant P‐values.

Abbreviations: CCF, congestive cardiac failure; eGFR, estimated glomerular filtration rate; FiO2, fraction of inspired oxygen; IHD, ischaemic heart disease; OR, odds ratio.

*

P <0.05;

**

P <0.01 for the independent logit coefficient or OR.