TABLE 3.
Outcome b | Outcome score at long‐term follow‐up c , median (IQR) | Association between the total attributable persistent COVID‐19 symptom burden score and outcome, adjusted odds ratio (95% CI) |
---|---|---|
Overall health status measured by EQ‐VAS | 78 (60, 89) | 0.63 (0.57–0.69) |
Quality of life measured by EQ‐5D‐5L | 0.90 (0.79, 1.00) | 0.65 (0.59–0.72) |
Psychological stress measured by PHQ‐4 | 2 (0, 4) | 1.40 (1.28–1.54) |
Abbreviations: IQR = interquartile range, EQ‐VAS = EuroQol Visual Analog Scale; PHQ‐4 = Patient Health Questionnaire‐4.
The association between the total attributable persistent COVID‐19 burden score (a measure of burden of persistent COVID‐19 symptoms) and each outcome was analyzed using multivariable proportional odds regression. This table includes 213 participants who responded to Part 2 of the long‐term follow‐up survey.
Overall health status was measured using the EuroQol visual analogue scale (EQ‐VAS), which asked participants to rate their health from 0 (worst health) to 100 (best health). Quality of life was measured with the EQ‐5D‐5L, which measures the participant's mobility, self‐care, activities, pain, and anxiety, and is summarized with a utility score ranging from <0 (worse than death) to 1.0 (perfect health). Psychological distress was measured with the Patient Health Questionnaire‐4 (PHQ‐4), a 4‐item questionnaire that grades the severity of depression and anxiety and ranges from 0 (no symptoms) to 12 (severe psychological distress).
Long‐term follow‐up was 6–11 months after the first positive SARS‐CoV‐2 test.