Table 4.
Clinical features of children with NF1 and OPG.
| Clinical features | Number of patients | % |
|---|---|---|
| ADHDa | 19 | 12.7 |
| Audiological deficits | 2 | 1.3 |
| Endocrinopathy | 29 | 19.3 |
| Epilepsy | 8 | 5.3 |
| Learning disabilities | 65 | 43.3 |
| Neurological deficits | 13 | 8.7 |
| Other mental disorders | 10 | 6.7 |
| Second malignancy | 2 | 1.3 |
| Vasculopathy | 10 | 6.7 |
| Visual deficits | 29 | 19.3 |
Children with NF1 and OPG showed variable clinical features, which were documented at their last visit. Some of the children had acquired multiple diagnosis over their course of disease. Vasculopathies included two children with Moyamoya syndrome after radiation, three patients with a stroke after surgery, 3 patients with cerebral vasculopathies not otherwise specified, but without strokes, and 2 patients with renal artery stenosis.
aAttention deficit hyperactivity disorder.