Table 2.

Total TPM (transcripts per million) in each functional category for the differentially expressed transcripts in CERM (Coxiella endosymbiont from R. microplus)-free metanymphs.

Sum of TPM in CERM and CERM-free metanymphs grouped into functional categories
Category	CERM	CERM-free	Regulation pattern
Secreted/protease inhibitor	24078.64	4937.82	UNDER
Secreted/evasin	2460.52	158.63	UNDER
Secreted/metalloprotease	2373.48	1219.23	UNDER
Detoxification/oxidation	1278.55	1245.03	UNDER
Protein synthesis	986.93	280.05	UNDER
Transposon	674.3	131.88	UNDER
Energetic metabolism	535.7	200.29	UNDER
Basic tail protein	315.75	52.37	UNDER
Ixodegrin	268.89	88.74	UNDER
Secreted/DAP-36	233.86	17.12	UNDER
Secreted/8.9	204.17	1.32	UNDER
Extracellular matrix	35552.83	49671.50	OVER
Immunity	3841.65	17208.42	OVER
Carbohydrate metabolism	2548.87	8705.11	OVER
Secreted/lipocalin	4208.02	5421.52	OVER
Nucleotide metabolism	766.46	4452.99	OVER
Lipid metabolism	3659.48	4316.08	OVER
Signal transduction	1455.77	4189.93	OVER
Protein modification	1212.22	3697.05	OVER
Secreted/protease	2383.11	3373.91	OVER
Cytotoxin	1150.83	2937.87	OVER
Transporters and receptors	1309.5	2607.53	OVER
Detoxification	835.30	1740.97	OVER
Transcription machinery	508.04	1610.77	OVER
Protein export	1363.44	1410.07	OVER
Secreted/mucin	375.89	1307.63	OVER
Nuclear regulation	165.40	1138.48	OVER
Cytoeskeletal	164,81	1014.25	OVER
Proteasome	379.20	753.54	OVER
Amino-acid metabolism	205.76	737.19	OVER
Transcription factor	57.11	181.83	OVER
Storage	12.79	136.03	OVER
Nuclear export	22.67	102.24	OVER
Intermediate metabolism	2.44	14.42	OVER
Total	95592.38	125061.81

UNDER, Underexpressed categories in CERM-free metanymphs; OVER, overexpressed categories in CERM-free metanymphs.