TABLE 2.

Evaluation of patients with previous severe reactions after PEG/PEG‐derivative medications

No.	Age in years	Sex	History of allergy	SPT with PEG and PEG derivatives	Vaccination outcome (all patients were vaccinated with Comirnaty vaccine)
28	40–50	F	Suspected anaphylaxis to naproxen and omeprazole	Negative	No reaction
29	60–70	F	Anaphylaxis to steroid injection	Negative	No reaction
30	80–90	F	Suspected anaphylaxis to radiocontrast agent; skin rash and swelling from make‐up products	Negative	No reaction
31	70–80	F	Anaphylaxis to paclitaxel	Negative	No reaction
32	30–40	F	Anaphylaxis to paclitaxel	Negative	No reaction
33	50–60	F	Anaphylaxis to tetanus vaccine	Negative	No reaction
34	40–50	F	Anaphylaxis to muscle relaxant containing polyethylene glycol	Negative	No reaction
35	50–60	F	Anaphylaxis to radio contrast media, omeprazole, penicillin, cephalosporin, erythromycin. Red eyes from eye drops containing PEG. Vomiting from laxative.	Negative	Late onset maculopapular exanthema (mild)
36	70–80	F	Anaphylaxis to different vaccines (tetanus, polio, mumps)	Negative	No reaction
37	50–60	F	Urticaria to penicillin, angioedema to influenza vaccine, large local reactions to ointments containing polyethylene glycol	Negative	No reaction

Abbreviations: F, female; M, male, SPT is skin prick test.