TABLE 1.

Patient characteristics at admission (<72 h) by ventilation status at the time of sampling. Data are expressed as median and interquartile range. Statistical differences between groups are expressed as P values (Mann Whitney U test or Fisher's exact test). Reference intervals for CLEIA were: sTM 6.9–14.5 TU/mL, TAT 0.40–3.25 ng/mL, tPAI‐C 2.23–18.72 ng/mL and PIC 0.293–1.319 μg/mL

Variable	Ventilated (n = 20)	CPAP (n = 34)	Not ventilated (n = 50)	P value ventilated v CPAP	P value ventilated v not ventilated	P value CPAP v not ventilated
Age	59 (44–73)	66 (46–72)	49 (42–65)	NS	NS	NS
Female	11 (55%)	17 (50%)	22 (44%)	NS	NS	NS
Days in hospital	13 (9–20)	6 (4–13)	12 (1–19)	NS	NS	NS
PT (s)	11.4 (10.9)	11.3 (10.8–12.6)	10.9 (10.5–11.5)	NS	.03	.005
APTT (s)	27.4 (25.2–32.9)	28.6 (25.0–32.1)	25.4 (24.1–29.5)	NS	NS	NS
Fibrinogen (g/L)	5.33 (3.74–6.32)	6.22 (4.77–7.66)	5.40 (4.45–6.68)	NS	NS	NS
D‐dimer (mg/L)	6.55 (2.08–42.27)	1.56 (0.80–5.680	0.71 (0.42–0.94)	.008	<.0001	.0003
FDP (mg/mL)	13.9 (6.7–81.5)	4.9 (2.9–17.8)	2.7 (2.5–4.1)	.02	<.0001	.002
Antithrombin (IU/mL)	79.0 (72.8–100.7)	95.4 (84.6–107.4)	96.6 (83.0–104.9)	NS	NS	NS
WBC	9.2 (7.3–14.8)	8.4 (5.4–11.5)	6.8 (4.9–8.8)	NS	.003	.008
Neutrophils x109/L	8.28 (5.67–13.17)	6.91 (4.31–10.74)	5.49 (3.73–7.09)	NS	.01	.03
Lymphocytes x109/L	0.77 (0.50–1.14)	0.75 (0.58–0.98)	0.91 (0.64–1.19)	NS	NS	NS
Platelets x109/L	218 (143–282)	239 (167–304)	236 (190–328)	NS	NS	NS
TAT (ng/mL)	18.1 (13.2–24.9)	13.2 (9.0–22.1)	9.4 (7.9–16.6)	<.006	<.0001	<.0001
sTM (TU/mL)	25.7 (8.6–79.4)	9.1 (5.9–16.5)	4.5 (2.9–7.1)	.05	.0005	NS
tPAI‐C (ng/mL)	24.1 (13.5–40.7)	19.4 (15.5–34.1)	16.8 (12.3–20.5)	NS	NS	NS
PIC (μg/mL)	2.475 (1.320–15.766)	2.220 (1.716–3.383)	1.683 (1.17–2.449)	NS	.04	.04