TABLE 4.
Multivariable analyses of hospitalized SARS‐CoV‐2‐infected patients with a BMI ≥25 with BMI and EOSS as categorical predictor variables
| AKI | ICU Admission | Mechanical Ventilation | Mortality | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| aOR | 95% CI | p value | aOR | 95% CI | p value | aOR | 95% CI | p value | aOR | 95% CI | p value | |
| Model 4 | ||||||||||||
| BMI ≥40 | 0.66 | 0.27–1.63 | .368 | 0.64 | 0.30–1.37 | .252 | 0.79 | 0.34–1.84 | .583 | 2.91 | 0.60–14.16 | .185 |
| BMI 30.00–39.99 | 0.63 | 0.36–1.09 | .0959 | 0.99 | 0.64–1.53 | .953 | 0.92 | 0.56–1.53 | .752 | 2.15 | 0.64–7.19 | .213 |
| BMI 25.00–29.99 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | ||||||||
| Model 5 | ||||||||||||
| EOSS 3/4 | 6.61 a | 3.83–11.40 a | <.001 a | 17.54 | 5.10–60.31 | <.001 | 3.10 a | 2.01–4.76 a | <.001 a | 4.40 a | 1.65–11.74 a | .00312 a |
| EOSS 2 | 6.61 a | 3.83–11.40 a | <.001 a | 10.86 | 3.28–36.01 | <.001 | 3.10 a | 2.01–4.76 a | <.001 a | 4.40 a | 1.65–11.74 a | .00312 a |
| EOSS 0/1 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | ||||||||
| Model 6 | ||||||||||||
| BMI ≥40 | 0.770 | 0.29–2.03 | .600 | 0.69 | 0.32–1.52 | .357 | 0.890 | 0.37–2.13 | .795 | 3.92 | 0.77–19.91 | .100 |
| BMI 30.00–39.99 | 0.73 | 0.41–1.32 | .297 | 1.00 | 0.64–1.57 | .994 | 1.020 | 0.610–1.72 | .933 | 2.70 | 0.79–9.26 | .115 |
| BMI 25.00–29.99 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | ||||||||
| EOSS 3/4 | 6.40 a | 3.71–11.05 a | <.001 a | 17.270 | 5.02–59.38 | <.001 | 3.10 a | 2.01–4.78 a | <.001 a | 5.05 a | 1.83–13.90 a | .00174 a |
| EOSS 2 | 6.40 a | 3.71–11.05 a | <.001 a | 10.710 | 3.23–35.51 | <.001 | 3.10 a | 2.01–4.78 a | <.001 a | 5.05 a | 1.83–13.90 a | .00174 a |
| EOSS 0/1 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | ||||||||
Note: Reference groups—Overweight (BMI 25.00–29.99) for WHO Categories of BMI and EOSS stage 0/1 for EOSS stage. Bolded aORs are statistically significant.
Abbreviations: AKI, acute kidney injury; aOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval; EOSS, Edmonton Obesity Staging System; ICU, Intensive Care Unit.
a
EOSS stage is considered as a continuous predictor variable due to zero counts, with the reference group being the stage below each stage examined (i.e. reference group for EOSS stage 3/4 is EOSS stage 2 and reference group for EOSS stage 2 is EOSS stage 0/1).