Fig. 6.

RNA sequencing of the repaired articular cartilages at week 12. (a) Principal component analysis (PCA) of the cartilage transcriptome from the normal, PAA-RGD, PEG-RGD, and GelMA groups. (b–c) Gene ontology (GO) pathway analysis of genes downregulated in the PAA-RGD group as relative to the GelMA (b) and PEG-RGD (c) groups. (d–e) KEGG pathway analysis of genes downregulated in the PAA-RGD group as relative to the GelMA (d) and PEG-RGD (e) groups. (f) Hierarchical clustering analysis using differentially expressed genes implied downregulated graft-versus-host disease pathways for the PAA-RGD group.