Table 1.

Demographic and clinical characteristics with postmortem AD indices of the participants

Characteristic	All (n = 1,585)
Demographic
Age at death, mean (SD) y	89.3 (6.7)
Age at the last clinical visit, mean (SD) y	88.4 (6.7)
Women, n (%)	1,060 (67%)
Non-Hispanic white, n (%)	1,498 (95%)
Education, mean (SD) years	16.3 (3.7)
Clinical & genetic
Any apolipoprotein ε4	403 (26%)
Hypertension, n (%)	1,054 (67%)
Diabetes mellitus, n (%)	342 (22%)
History of smoking, n (%)	490 (31%)
Number of vascular risk factors,* median (Q1–Q3)	1.0 (0–2)
Framingham risk score (FRS), mean (SD)	19.3 (3.2)
FRS-age component score, median (Q1–Q3)	15.0 (15–15)
FRS-Body mass index score, median (Q1–Q3)	1.0 (0–0)
FRS-Systolic blood pressure score, median (Q1–Q3)	3.0 (2–4)
FRS-Smoking score, median (Q1–Q3)	0.0 (0–0)
FRS-Diabetes mellitus score, median (Q1–Q3)	0.0 (0–0)
AD pathological indices
NIA-Reagan AD Pathological diagnosis, n (%)	1,020 (64%)
Square root of Aβ levels, mean (SD)	1.5 (1.1)
Square root of tau levels, mean (SD)	1.6 (1.3)

Number of vascular risk factors is a summary statistic of the count of hypertension, diabetes mellitus, and smoking present in a participant (1 point for each, with a total score range 0– 3).