Figure 1.

Changes in categorical classification of insulin dysregulation following treatment with dexamethasone. Graph A demonstrates that significantly more horses were classified as insulin dysregulation using the basal insulin following dexamethasone treatment. Graph B demonstrates that significantly more horses were classified as insulin dysregulation using the criteria of CGIT[Gluc]₄₅ returning to baseline blood [glucose]. Graph C demonstrates no statistical difference in the number of horses classified as insulin dysregulation based on the CGIT[Ins]₄₅ > 100 μIU/mL. Graph D demonstrates that significantly more horses were diagnosed with insulin dysregulation based on the OST[Ins]₆₀ > 45 μIU/mL. Graph E demonstrates that significantly more horses were diagnosed with insulin dysregulation based on OST[Ins]₆₀ > 60 μIU/mL.

^a Indicates significance from baseline time point; *P < 0.05.

AUC_gluc0–240 — Area under the glucose curve from 0 to 240 min; AUC_ins0–150 — Area under the insulin curve from 0 to 150 min; [Ins]₆₀ — Insulin concentration at 60 min; AUC_gluc0–150 — Area under the glucose curve from 0 to 150 min; PP-D_gluc — Positive phase duration of the glucose curve; [Ins]₄₅ — Insulin concentration at 45 min.