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Scheme showing the various stages (1–9) of the HIV lifecycle that the ARVs co-encapsulated in nanocarriers inhibit while aiming to achieve synergism. Abbreviations: CCR5, C–C chemokine receptor type 5; CD4, cluster of differentiation 4; INSTI, integrase strand transfer inhibitor; NNRTI, non-nucleoside reverse transcriptase inhibitor; and NRTI, nucleoside reverse transcriptase inhibitor.
