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. 2022 May 17;23:184. doi: 10.1186/s12859-022-04720-z

Fig. 6.

Fig. 6

Solid-cancer analysis of pathways that inform paclitaxel response. A GO Biological Processes pathway enrichment of genes contained within the top predictive modules. B Correlation of PTX response with expression of genes in ovarian cancer cell lines. C Max–min normalized gene expression of NOTCH3/PAX8 genes in ovarian cancer cell lines (left). Response to PTX in ovarian cancer cell lines separated by the expression of four genes shown in the heatmap on the left (right). Higher AUC means more resistant to drug