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. 2022 May 16;14:63. doi: 10.1186/s13148-022-01282-y

Table 2.

Top gene ontology terms for biological process in brain-enriched group

GOTERM_BP_ALLa Count p valueb Bonferronic FDR
GO:0099536 synaptic signalling 85 2.58E−16 1.42E−12 4.04E−13
GO:0098916 anterograde trans-synaptic signalling 85 2.58E−16 1.42E−12 4.04E−13
GO:0099537 trans-synaptic signalling 85 2.58E−16 1.42E− 2 4.04E−13
GO:0007268 chemical synaptic transmission 85 2.58E−16 1.42E−12 4.04E−13
GO:0055085 transmembrane transport 131 1.63E−12 1.04E−08 2.04E−09
GO:0007399 nervous system development 187 4.01E−12 2.56E−08 4.18E−09
GO:0048666 neuron development 100 9.98E−11 6.37E−07 8.92E−08
GO:0044708 single-organism behaviour 55 1.18E−10 7.55E−07 9.24E−08
GO:0030182 neuron differentiation 118 1.62E−10 1.03E−06 1.02E−07
GO:0006811 Ion transport 134 1.64E−10 1.05E−06 1.02E−07
GO:0048699 generation of neurons 125 6.82E−10 4.36E−06 3.85E−07
GO:0022008 neurogenesis 131 7.38E−10 4.72E−06 3.85E−07
GO:0034220 Ion transmembrane transport 96 1.96E−09 1.25E−05 9.41E−07
GO:0006836 neurotransmitter transport 33 1.25E−08 7.97E−05 5.29E−06
GO:0031175 neuron projection development 83 1.27E−08 8.10E−05 5.29E−06
GO:0030001 metal ion transport 81 4.83E−08 3.09E−04 1.78E−05
GO:0007610 Behaviour 62 4.84E−08 3.09E−04 1.78E−05
GO:0050804 modulation of synaptic transmission 39 8.38E−08 5.35E−04 2.91E−05
GO:0007267 cell–cell signalling 127 1.43E−07 9.12E−04 4.65E−05
GO:0044707 single-multicellular organism process 387 1.50E−07 9.59E−04 4.65E−05
GO:0098660 inorganic ion transmembrane transport 73 1.56E−07 9.96E−04 4.65E−05
GO:0007611 Learning or memory 33 1.79E07 0.001142057 4.93E05
GO:0042391 regulation of membrane potential 45 1.81E−07 0.001157197 4.93E−05
GO:0030030 cell projection organization 112 2.38E−07 0.00151699 6.20E−05
GO:0007275 multicellular organism development 326 2.77E−07 0.001767572 6.93E−05
GO:0006812 cation transport 89 4.60E−07 0.002937168 1.11E−04
GO:0050890 cognition 35 5.05E−07 0.003220477 1.17E−04
GO:0048812 neuron projection morphogenesis 58 5.53E−07 0.003527699 1.24E−04

aGOTERM_BP_ALL, DAVID gene ontology database; bp value, uncorrected p value; cBonferroni, corrected p value