Skip to main content
. Author manuscript; available in PMC: 2022 May 17.
Published in final edited form as: West J Nurs Res. 2016 May 24;38(9):1155–1184. doi: 10.1177/0193945916649954

Table 8.

Characteristics of the Intervention Studies in the Medication Category: Cognitive Outcome Domain.

Source n Intervention Duration Age Range (M ± SD) ADHD Diagnosis PA Measures/ Days Monitored Outcome Measures Medication Effect I&C Key Results

Butte, Treuth, Voigt, Llorente, and Heird (I999) a 31 (M = 26, F = 5) 2 months
Study 1: Day 1
Study 2: 2 months after Study 1
6–12 (9.5 ± 1.9) Yes Counts per minute by a Doppler microwave detector/19 hr Attention Energy expenditure Yes I (Study 2): Received different doses of stimulant medication
C (Study 1): No stimulant medication
Positive sig. correlation between errors of commission and decrease in TEE, AEE, movie EE attributable to the stimulant medication
Negative sig. correlation between response time and difference in TEE, AEE, total and awake activity incident to the stimulant medication
Konrad, Gunther, Heinzel-Gutenbrunner, & Herpertz-Dahlmann, 2005 a 44 (M = 37, F = 7) 6 days 8–12 (10.3 ± 1.9) Yes Actigraph/6 days Attention Inhibitory control Yes I: Medication (low dose and high dose)
C: Placebo
Sig. effects of MPH on total errors in Sustained Attention Task and SSRT
A sig. linear trend of MPH on Sustained Attention Task as well as a sig. quadratic trend for SSRT
Medina et al. (2010) a 25 (M = 25) 2 days 7–15 US (9.3 ± 2.9) NUS (9.8 ± 2.4) Yes None Sustained attention Yes I: 30-min treadmill exercise protocol
C: 1-min stretching session
No sig. differences on CPT between US and NUS samples
Sig. faster Hit RT/Hit RT ISI change in the PA group than control
Sig. lower perseverations in the PA group than control

Note. I = intervention; ADHD = attention-deficit/hyperactivity disorder; PA = physical activity; C = control; M = male; F = female; Sig. = significant; TEE = total energy expenditure; AEE = awake energy expenditure; EE = energy expenditure; MPH = methylphenidate; SSRT = stop-signal reaction time; US = methylphenidate users; NUS = nonmethylphenidate users; CPT = Conner’s Continuous Performance Test; RT = reaction time; ISI = interstimulus,

a.

Indicates study covered more than one domain and results of other domain are listed in their respective tables.