FIG 1.

Distribution of ceftolozane-tazobactam, ceftazidime-avibactam, and imipenem-relebactam MIC values against all P. aeruginosa isolates and resistant subsets. C/T, ceftolozane-tazobactam; IMR, imipenem-relebactam; CZA, ceftazidime-avibactam; MDR, multidrug resistant (resistant to ≥3 sentinel agents [amikacin, aztreonam, cefepime, colistin, imipenem, levofloxacin, and piperacillin-tazobactam]); pan-β-lactam-nonsusceptible, nonsusceptible to all tested β-lactams (excluding C/T, IMR, and CZA); DTR, difficult-to-treat resistance (nonsusceptible to all tested β-lactams [excluding C/T, IMR, and CZA] and fluoroquinolones). Dashed lines indicate the respective susceptible breakpoints. Arrows indicate the mode of the respective MIC distributions.