TABLE 2.

Genomic characteristics of KPC-producing Klebsiella pneumoniae strains^a

Isolate	ST	Antimicrobial resistance determinants		Porins			blaKPC copy no.
		Beta-lactam	Aminoglycosides	ompK35	ompK36	Plasmid_replicons (InC)
KPC-KP_TO1	512	blaKPC-3, blaTEM1A, blaOXA-9	aadA2b, aac(6’)-Ib-cr	Truncated at aa 41	GD insertion at aa 134-135	ColRNAI, IncFIB (pQIL), IncFII(K)	1b
KPC-KP_TO3	512	blaKPC-66, blaTEM1A, blaOXA-9	aadA2b, aac(6’)-Ib-cr	Truncated at aa 41	GD insertion at aa 134-135	ColRNAI, IncFIB (pQIL), IncFII(K)	0,85
KPC-KP_TO5	512	blaKPC-3, blaTEM1A, blaOXA-9	aadA2b, aac(6’)-Ib-cr	Truncated at aa 41	Truncated at aa 310	ColRNAI, IncFIB (pQIL), IncFII(K)	4,59

^aST, sequence type; ND, not determined; GD, glycine and aspartic acid.

^bUsed as reference strain.