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Effect of hepcidin25 on the dynamics of spike subunits. (A) Docked binding sites of hepcidin25 on chain C. (B) Measured angle is reported for Chain C, chain C with hepcidin25 in AMR (CH), chain C in association with ACE2 (CD), and hepcidin25 bonded to AMR of chain C in complex with ACE2 (CDH). (C) Results of hepcidin25 binding to chain C in association with other subunit chains and ACE2 (ABCD-HPC) or without hepcidin25 (ABCD).
