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. 2022 May 10;7(20):17024–17042. doi: 10.1021/acsomega.2c00154

Figure 6.

Figure 6

Intrinsic dynamics of S proteins in closed, open, and bound states. (A) Overlap of 10 ANM modes between the closed and open states. (B) Overlap of 10 ANM modes between the open and bound states. (C) The square fluctuations of S proteins in three states based on the first ANM modes. The bounded RBD is most stable in the closed state (blue) but has the largest flexibility in the open state (green). The bounded RBD in the complex state has the lowest stability (red).