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. 2022 May 10;7(20):17024–17042. doi: 10.1021/acsomega.2c00154

Table 1. Hinge Sites in the SARS-CoV2 Spike–ACE2 Complex.

chain A B C D
hinge sites 317N, 326I, 474Q, 475A, 477S, 479P, 485G, 487N, 488C, 533L, 543F, 545G, 578D, 582L, 595 V, 612Y, 620 V, 621P, 623A, 643F, 650L, 654Z, 664I, 673S, 693I, 730S, 735S, 742I, 743C, 746D, 761T, 780Z, 783A, 854 K, 856N, 858L, 860 V, 873Y, 949L, 986P, 991 V, 1005Q, 1058H 14Q, 33T, 37Y, 55F, 56L, 59F, 221S, 272P, 295P, 309Z, 322P, 590C, 698S, 752L, 753L, 758S, 971G, 983R, 990Z, 1146D 320 V, 369Y, 371S, 472I, 489Y, 591S, 658N, 662C, 667G, 671C, 695Y, 703N, 730S, 776 K, 826 V, 866T, 948L, 966L, 996L, 1013I, 1015A, 1146D 19S, 31K