Table 3. Allosteric Modulation Region in the Equilibrated Spike–ACE2 + Hepcidin Complex^a.

name	position	P
PHE	342	0.61
ASN	343	0.36
ALA	344	0.36
THR	345	0.56
ARG	346	0.31
TRP	353	0.61
ASN	354	0.84
ARG	355	0.31
LYS	356	0.27
PHE	374	0.40
SER	375	0.56
THR	376	0.56
ASP	398	0.51
SER	399	0.66
PHE	400	0.33
VAL	401	0.19
VAL	407	0.23
PRO	412	0.56
LYS	424	0.19
LEU	425	0.56
PRO	426	0.64
ASP	427	0.75
THR	430	0.19
VAL	433	0.19
ILE	434	0.36
ALA	435	0.64
TRP	436	0.80
ASN	437	0.75
TYR	508	0.1736
ARG	509	0.5950
VAL	510	0.79
VAL	511	0.3306
VAL	512	0.1900

^aAll residues are located in the C chain. In italic font type the most competent residues in intermodule communication (P ≥ 0.75) are given.