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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Life Sci. 2022 Mar 31;298:120524. doi: 10.1016/j.lfs.2022.120524

Figure 2.

Figure 2.

Representative action potential (AP) recordings in bladder afferent neurons from mice. A, B: Excitability of bladder afferent neurons was significantly increased in SCI mice, evident as lower thresholds of APs(A) and multiple firing pattern(B). These SCI-induced changes were significantly reversed in the SCI+NGF-Ab group. C: Bath application of tetrodotoxin (TTX) partly inhibited the AP of bladder afferent neurons in SI mice whereas it almost completely inhibited the AP in SCI mice, but not in SCI+NGF-Ab mice.