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. 2021 Nov 17;43(3):469–506. doi: 10.1210/endrev/bnab029

Table 3.

Public health strategies to prevent and control iodine deficiency in lactating women, infants and toddlersa

Iodine status in the general populationb Status of salt iodization in population Recommended strategies
Lactating women Infants (age 0-6 mo) Toddlers (age 7-24 mo)
Adequate iodine nutrition (≥ 100 µg/L) Effective and sustained salt iodization • Maintain salt iodization • Exclusive breastfeeding • Maintenance of breastfeedingc
• Formula-fed infants should receive formula milk fortified with iodine • Complementary foods and/or follow-up formula fortified with iodine
• Iodized salt in complementary foods from age > 12 mo
Mild-to-moderate iodine deficiency (20-99 µg/L) Incomplete coverage of iodized salt • Improve coverage of iodized salt • Exclusive breastfeeding • Maintenance of breastfeedingc
• Daily iodine supplementation • Formula fed infants should receive formula milk fortified with iodine • Complementary foods and/or follow-up formula, MNP/LNS fortified with iodine
• Iodized salt in complementary foods from age > 12 mo
Severe iodine deficiency (< 20 µg/L) No or poor coverage of iodized salt • Introduce salt iodization • Exclusive breastfeeding • Maintenance of breastfeedingc
• Daily iodine supplementation or single annual oral dose of 400-mg iodized oil • Formula fed infants should receive formula milk fortified with iodine • Complementary foods and/or follow-up formula, MNP/LNS fortified with iodine

Abbreviations: LNS, lipid-based nutrient supplements; MNP, micronutrient powders; UIC, urinary iodine concentration.

a Adapted with permission from (21):

b Defined as median UIC in 6- to 12-year-old children (176). Median UIC thresholds for general population/women of reproductive age uncertain (309).

c Continue frequent on-demand breastfeeding until age 2 years or older.