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. 2021 Feb 4;48(1-2):kuab009. doi: 10.1093/jimb/kuab009

Fig. 2.

Fig. 2.

MEP and MVA pathways. (a) Related enzymes in the MEP pathway and MVA pathway. AACT, acetoacetyl CoA thiolase gene; HMGS, HMG-CoA synthase gene; HMGR, HMG-CoA reductase gene; MK, mevalonate kinase gene; PMK, phosphomevalonate kinase gene; MDC, 5-pyrophosphate methyl hydrovalerate decarboxylase gene; DXS, deoxyxylulose-5-phosphate synthase gene; DXR, deoxyxylulose-5-phosphate isomerase gene; MCT, 2-C-methyl-d-erythritol-4-cytidine monophosphate acyltransferase gene; CMK, 4-(5′-cytidine pyrophosphate)-2-C-methyl erythritol kinase gene; MDS, 2-C-methyl-erythritol-2,4-cyclic pyrophosphate synthetase gene; HDS, (E)-4-hydroxy-3-methylbutane-2-enyl diphosphate synthase gene; HDR, (E)-4-hydroxy-3-methylbutan-2-enyl diphosphate reductase gene. (b) Enzymes in the synthesis pathway of terpenoids. IDI, isoprene pyrophosphate isomerase; GPPS, geranyl diphosphate synthase gene; FPPS, farnesyl diphosphate synthase gene; GGPPS, geranylgeranyl diphosphate synthase gene; SS, squalene synthase.