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. Author manuscript; available in PMC: 2022 May 17.
Published in final edited form as: Cell Rep. 2022 Feb 15;38(7):110375. doi: 10.1016/j.celrep.2022.110375

Figure 6. Model of LGL1 function during vertebrate epithelial migration and branching morphogenesis.

Figure 6.

(A) Schematic diagram of the developing mammary gland at the post-pubertal stages during which active branching is occurring. The terminal end buds (TEB) develop at the onset of puberty (3 weeks after birth) at the distal tip of each primary duct. Proximal is to the left and distal to the right.

(B) Modulation of Integrin β1 signaling levels is essential for vertebrate directional migration.

(C) Model of the role of directional migration during invertebrate and vertebrate branching.