Figure 1.

CNV and sequence alteration contribute to abnormal m⁷G-Regulator Levels. (A) CNV strongly correlates to gene expression of m⁷G regulators in pan-cancer using Pearson analysis. (B) Heterozygous and homozygous amplification/deletion of m⁷G regulators in pan-cancer. Amplification, red; Deletion, blue. (C) The location of CNV of m⁷G regulators on 23 chromosomes. (D) CNV of m⁷G regulators in TCGA-ccRCC dataset. CNV loss, blue; CNV gain, red; none CNV, green. (E) Mutation frequency of m⁷G regulators in pan-cancer.