Figure 6.

Bone marrow activation in the presence of vascular ¹⁸F-fluorodeoxyglucose uptake is associated with higher atherosclerotic plaque volume. Participants with co-occurring bone marrow activation and vascular ¹⁸F-fluorodeoxyglucose uptake had a significantly higher plaque burden than those with bone marrow activation but no vascular ¹⁸F-fluorodeoxyglucose uptake. The upper panel shows atherosclerotic plaque volume (mm³) in the group with bone marrow activation and vascular uptake (orange bar) and in the group with bone marrow activation without vascular uptake (blue bar). The mid-panel shows the comparison of adjusted odds ratios and 95% confidence interval for the different models. *In Model 3, 105 participants taking lipid-lowering therapies were eliminated. The lower panel shows representative magnetic resonance images of atherosclerotic plaques.