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. 2021 Oct 15;32(10):2245–2253. doi: 10.1093/cercor/bhab353

Table 2.

Comparisons of DLPFC measures among diagnostic groups

HC (n = 74) ARMS-NP (n = 55) ARMS-P (n = 18) ANCOVAa
Diagnosis Hemisphere Hemisphere × diagnosis
Measures Mean SD Mean SD Mean SD F P F P F P
Left DLPFC thickness (mm) 3.50 0.72 3.14 0.62 3.42 0.64 2.133 0.122 0.010 0.921 1.557 0.214
Right DLPFC thickness (mm) 3.65 0.69 3.35 0.65 3.30 0.79
Left DLPFC volume (mm3) 25 479 6231 27 500 5311 26 119 6782 1.983 0.142 0.774 0.380 3.799 * , ** 0.025
Right DLPFC volume (mm3) 27 383 6905 28 546 5605 24 048 7400
Left DLPFC area (mm2) 3167 1008 2994 929 3026 1032 2.137 0.122 0.089 0.766 0.337 0.715
Right DLPFC area (mm2) 2979 1197 3177 944 2804 996

DLPFC, dorsolateral prefrontal cortex.

a

Age, gender, ICV, use of antipsychotics, and scanning site were entered as covariates.

*Post hoc tests showed that volume was reduced on the right hemisphere in ARMS-P subjects compared with ARMS-NP (P = 0.042) and HC (P = 0.028) groups.

**A rightward laterality (left < right) was seen only in HC (P = 0.003).