Table 2.
HC (n = 74) | ARMS-NP (n = 55) | ARMS-P (n = 18) | ANCOVAa | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Diagnosis | Hemisphere | Hemisphere × diagnosis | ||||||||||
Measures | Mean | SD | Mean | SD | Mean | SD | F | P | F | P | F | P |
Left DLPFC thickness (mm) | 3.50 | 0.72 | 3.14 | 0.62 | 3.42 | 0.64 | 2.133 | 0.122 | 0.010 | 0.921 | 1.557 | 0.214 |
Right DLPFC thickness (mm) | 3.65 | 0.69 | 3.35 | 0.65 | 3.30 | 0.79 | ||||||
Left DLPFC volume (mm3) | 25 479 | 6231 | 27 500 | 5311 | 26 119 | 6782 | 1.983 | 0.142 | 0.774 | 0.380 | 3.799 * , ** | 0.025 |
Right DLPFC volume (mm3) | 27 383 | 6905 | 28 546 | 5605 | 24 048 | 7400 | ||||||
Left DLPFC area (mm2) | 3167 | 1008 | 2994 | 929 | 3026 | 1032 | 2.137 | 0.122 | 0.089 | 0.766 | 0.337 | 0.715 |
Right DLPFC area (mm2) | 2979 | 1197 | 3177 | 944 | 2804 | 996 |
DLPFC, dorsolateral prefrontal cortex.
Age, gender, ICV, use of antipsychotics, and scanning site were entered as covariates.
*Post hoc tests showed that volume was reduced on the right hemisphere in ARMS-P subjects compared with ARMS-NP (P = 0.042) and HC (P = 0.028) groups.
**A rightward laterality (left < right) was seen only in HC (P = 0.003).