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. 2022 Feb 9;106(5):1000–1010. doi: 10.1093/biolre/ioac015

Figure 1.

Figure 1

Irx3LacZ/LacZ causes deficits in uterine vascularization and subfertility. (A) H&E staining of D7 wild type (WT, n = 6) and Irx3LacZ/LacZ (n = 6) pregnant uteri. Scale bars, 250 mm. The white boxes are enlarged in the images below each section. AM: anti-mesometrial; M: mesometrial; E: embryo. (B, C) Circulating estradiol (B) and progesterone (C) were measured at D7 of gestation (WT, n = 10; Irx3LacZ/LacZ, n = 6). (D) Average number of implantation sites in utero at D7 (WT n = 8; Irx3LacZ/LacZ n = 7) and D11 (WT n = 3; Irx3LacZ/LacZ n = 5). Data in D represent the mean ± SEM. Statistics: two-sample t-test, *: P < 0.05; **: P < 0.01.