Table 5.
PFAS chemicals identified in this SEM that had at least one animal or human study summarized in the literature inventory.
| Chemical name | CASRN | Animal evidence | Human evidence |
|---|---|---|---|
| 1-Butanesulfonic acid, 1,1,2,2,3,3,4,4,4-nonafluoro-, salt with sulfonium, dimethylphenyl- (1:1) | 220133-51-7 | X | — |
| 1H,1H,2H-Perfluorocyclopentane | 15290-77-4 | X | — |
| 1H,1H,5H-Perfluoropentanol | 355-80-6 | X | — |
| 2-Chloro-1,1,1,2-tetrafluoroethane | 2837-89-0 | X | — |
| 3,3,4,4,5,5,6,6,6-Nonafluorohexene | 19430-93-4 | X | — |
| 3-Methoxyperfluoro(2-methylpentane) | 132182-92-4 | X | — |
| 6:2 Fluorotelomer alcohol | 647-42-7 | X | — |
| 6:2 Fluorotelomer methacrylate | 2144-53-8 | X | — |
| 6:2 Fluorotelomer sulfonic acid | 27619-97-2 | X | X |
| 8:2 Fluorotelomer alcohol | 678-39-7 | X | X |
| Dodecafluoroheptanol | 335-99-9 | X | — |
| Methyl perfluoro[3-(1-ethenyloxypropan-2-yloxy)propanoate] | 63863-43-4 | X | — |
| Nafion | 31175-20-9 | X | X |
| N-Ethyl-N-(2-hydroxyethyl)perfluorooctanesulfonamide | 1691-99-2 | X | — |
| N-Ethylperfluorooctanesulfonamide | 4151-50-2 | X | — |
| N-Methyl-N-(2-hydroxyethyl)perfluorooctanesulfonamide | 24448-09-7 | X | — |
| Perfluamine | 338-83-0 | X | — |
| Perfluoro(4-methoxybutanoic) acid | 863090-89-5 | X | — |
| Perfluoro(N-methylmorpholine) | 382-28-5 | X | — |
| Perfluoro(propyl vinyl ether) | 1623-05-8 | X | — |
| Perfluoro-1,3-dimethylcyclohexane | 335-27-3 | X | — |
| Perfluoro-1-iodohexane | 355-43-1 | X | — |
| Perfluoro-2,5-dimethyl-3,6-dioxanonanoic acid | 13252-14-7 | X | X |
| Perfluoro-3-methoxypropanoic acid | 377-73-1 | X | |
| Perfluoro-3-(1H-perfluoroethoxy)propane | 3330-15-2 | X | — |
| Perfluorobutanesulfonyl fluoride | 375-72-4 | X | — |
| Perfluorocyclohexanecarbonyl fluoride | 6588-63-2 | X | — |
| Perfluoroheptanesulfonate | 146689-46-5 | — | X |
| Perfluoroheptanesulfonic acid | 375-92-8 | — | X |
| Perfluoroheptanoic acid | 375-85-9 | — | X |
| Perfluoromethylcyclopentane | 1805-22-7 | X | — |
| Perfluorooctanesulfonamide | 754-91-6 | X | X |
| Perfluorooctanesulfonyl fluoride | 307-35-7 | X | X |
| Perfluoropentanoic acid | 2706-90-3 | X | X |
| Perfluoropropanoic acid | 422-64-0 | — | X |
| Perfluorotetradecanoic acid | 376-06-7 | X | X |
| Perfluorotridecanoic acid | 72629-94-8 | X | X |
| Perfluoroundecanoic acid | 2058-94-8 | X | X |
| Sodium perfluorodecanesulfonate | 2806-15-7 | — | X |
| Tetrabutylphosphonium perfluorobutanesulfonate | 220689-12-3 | X | — |
| Tetraethylammonium perfluorooctanesulfonate | 56773-42-3 | X | — |
| Trichloro((perfluorohexyl)ethyl)silane | 78560-45-9 | X | — |
| Triethoxy((perfluorohexyl)ethyl)silane | 51851-37-7 | X | — |
| Trifluoroacetic acid | 76-05-1 | X | X |
| Trifluoromethanesulfonic acid | 1493-13-6 | X | — |
Note: For perfluoroheptanoic acid and perfluoroundecanoic acid, data are only current through December 2019 because these PFAS were inadvertently excluded in the 2020 and 2021 literature search updates. —, no studies summarized in the literature inventory; CASRN, Chemical Abstracts Service Registry Number; PFAS, per- and polyfluoroalkyl substances; SEM, systematic evidence map; X, at least one study summarized in the literature inventory. An interactive visual summary of the information extracted in the literature inventory can be found in Tableau.53 For the most current information, please visit the web-based HAWC project page.45