Table 1.
Effect of Different Doses of Azilsartan on Gastric Lesion Area, Gastric Lesion Index and Percentage of Lesion Inhibition
Experimental Groups N=6 | Total Stomach Area (mm) | Gastric Lesion Area (mm) | Gastric Lesion Index | Lesion Inhibition % |
---|---|---|---|---|
Positive control | 37.4 | 3.07a | 8.2a | – |
Lansoprazole 30mg/kg | 44.55 | 1.35b | 3.04b | 62.96 |
Azilsartan 1mg/kg | 34.65 | 2.59a | 7.49c | 8.75 |
Azilsartan 5mg/kg | 31.98 | 2.28c | 7.13d | 13.16 |
Azilsartan 10mg/kg | 30.72 | 1.42b | 4.63e | 43.63 |
Notes: All values of lesion analysis were estimated in mean average, each value represents the mean of eight animals (n=8). Statistical comparison among groups: Mean values with different letters (a,b,c,d,e) have significant differences at (P < 0.05).