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. 2022 May 3;12:894836. doi: 10.3389/fcimb.2022.894836

Table 1.

Prevalence of HBV infection in gastric cancer patients and controls.

Variables Control (n=930) Gastric cancer (n=465)
no. (%) no. (%) Univariate analysis Multivariate analysis
OR (95% CI) P OR (95%CI) P
Age 61.42 ± 13.12 61.80 ± 10.17 NA 0.830  NA   NA
Gender        
 Female 478 (51.40) 129 (27.74) 1 1
 Male 452 (48.60) 336 (72.26) 2.75 (2.17-3.50) 0.000 2.64 (2.07-3.36) 0.000
HBsAg
Negative 862 (92.69) 404 (86.88) 1 1
 Positive 68 (7.31) 61 (13.12) 1.91 (1.33-2.76) 0.001 1.62 (1.03-2.55) 0.039
Anti-HBs    
 Negative 436 (46.88) 213 (45.81) 1 1
 Positive 496 (53.12) 252 (54.19) 1.04(0.83-1.30) 0.719 1.02 (0.77-1.35) 0.909
HBeAg    
 Negative 928 (99.78) 463 (99.57) 1 1
 Positive 2 (0.22) 2 (0.43) 1.00 (0.18-5.47) 0.999 0.84 (0.15-4.78) 0.839
Anti-HBe    
 Negative 727 (63.98) 242 (52.47) 1 1
 Positive 335 (36.02) 221 (47.53) 1.46 (1.17-1.83) 0.001 1.23 (0.94-1.61) 0.139
Anti-HBc    
 Negative 489 (52.58) 203 (43.66) 1 1
 Positive 441 (47.42) 262 (56.34) 1.43 (1.14-1.79) 0.002 1.28 (1.00-1.64) 0.047

CI, confidence interval; OR, odds ratio; Control, patients admitted to the orthopedics and ear, nose and throat departments of the hospital, unrelated to HBV; NA, not available.

Bold values indicate statistically significant difference.