Figure 4.

Expression of KISS1R during human osteoclastogenesis. Gene expression of KISS1R across different stages of human osteoclastogenesis, according to number of days of RANKL (25 ng/mL) stimulation, with osteoclast specific genes, OSCAR and CTSK in mature osteoclasts. KISS1R expression is identified throughout osteoclastogenesis. Each gene is normalized to gene length and the number of reads sequenced per sample. Each dot represents 1 donor. Only expression data within the detectable range is plotted. RPKM: reads per kilobase million, n = 8 donors.