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. 2022 Mar 4;107(6):1529–1540. doi: 10.1210/clinem/dgac117

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© The Author(s) 2022. Published by Oxford University Press on behalf of the Endocrine Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 9. — Effects of peripheral kisspeptin administration (intravenous 1 nmol/kg/hour) on circulating reproductive hormone levels in humans. Kisspeptin administration increased circulating levels of (A) kisspeptin (****P < .0001) and (B) luteinizing hormone (LH, ****P < .0001), compared with placebo. (B) Kisspeptin administration had no effect on follicle stimulating hormone (FSH) or (C) testosterone levels. Data shown as mean ± SEM, ****P < .0001, mixed-model analysis of variance, n = 26 healthy men.