Table 3.
Cumulative incidence function analysis of major osteoporotic fractures for each clinical risk factor
| Fracture events: 304 MOF fractures/competing events: 122 deaths | ||||
|---|---|---|---|---|
| MOF fractures CRF | Event, n (%) | 5-year CIF, % | P-value | n total |
| Age group | <0.0001 | 3560 | ||
| ≤67 years | 62 (20.4) | 4.9 | ||
| 68-75 years | 103 (33.9) | 8.1 | ||
| ≥76 years | 139 (45.7) | 15.1 | ||
| Obesity | 0.01 | 3560 | ||
| Yes | 45 (14.8) | 6.8 | ||
| No | 259 (85.2) | 9 | ||
| History of fracture | <0.0001 | 3533 | ||
| Yes | 137 (45.1) | 14.1 | ||
| No | 167 (54.9) | 6.6 | ||
| History of falls | 0.03 | 3531 | ||
| Yes | 83 (27.7) | 12.1 | ||
| No | 217 (72.3) | 7.7 | ||
| Comorbidities | 0.001 | 3560 | ||
| Yes | 48 (15.8) | 11.6 | ||
| No | 256 (84.2) | 8.3 | ||
| Early nonsubstituted menopause | 0.01 | 3549 | ||
| Yes | 20 (6.6) | 10.6 | ||
| No | 283 (93.4) | 8.5 | ||
| BMD status | <0.0001 | 3498 | ||
| Osteoporosis | 86 (29.4) | 18.5 | ||
| Osteopenia | 165 (56.3) | 8.8 | ||
| Normal | 42 (14.3) | 3.8 | ||
| T-score hip | <0.0001 | 3457 | ||
| ≤−2.5 | 29 (10) | 28.6 | ||
| >−2.5 TS | 261 (90) | 7.9 | ||
| T-score femoral neck | <0.0001 | 3457 | ||
| ≤−2.5 | 47 (16.2) | 22.17 | ||
| >−2.5 | 243 (83.8) | 7.6 | ||
| T-score spine | <0.0001 | 3452 | ||
| ≤−2.5 | 51 (17.6) | 16.2 | ||
| >−2.5 | 239 (82.4) | 7.7 |
Abbreviations: BMD, bone mineral density; CRF, clinical risk factor; MOF, major osteoporotic fractures.