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. 2021 Sep 29;122(4):552–559. doi: 10.1055/a-1549-6556

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 2 — Results of apixaban concentrations within the first 3.5 days after admission in patients without early re-exposure to apixaban. Patients reaching the 30-day in-hospital mortality are marked by red lines. Thick lines show the line corresponding to the exponential decay from a model that includes the effects and interactions of the treatment groups. Vertical axes are scaled logarithmically. Patients with major bleeding: n = 38, 113 apixaban concentration measurements; Patients with urgent surgery: n = 22, 108 apixaban concentration measurements.