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Clinical assessment of new bone formation. Results of new bone formation are shown using the same box-and-whisker plot representation as in Fig. 2. The new bone formation rate was measured using X-ray images at 1 month, 3 months, 6 months, and 9 months (n = 12). *p < 0.0001, †p < 0.001, ‡p < 0.025, with the use of a one-sample t-test based on the closed testing procedure.
