Table 2.
Adverse events.
| Adverse events | Severity (N = 12) | ||
|---|---|---|---|
| Grade 1 | Grade 2 | Grade 3 | |
| Pain at the site of cell transplantation within a week of transplantation | 2 (16.7%) | 10 (83.3%) | – |
| Discomfort at the site of cell transplantation after more than a week of transplantation | 3 (25.0%) | – | – |
| C-reactive protein increased | 2 (16.7%) | – | – |
| Temporary inflammation of gingival tissue | 1 (8.3%) | 1 (8.3%) | – |
| Angular stomatitis | – | 1 (8.3%) | – |
| Occlusal pain | – | 1 (8.3%) | – |
| Stomatitis | 1 (8.3%) | – | – |
| Temporary necrosis of gingival epithelium | 1 (8.3%) | – | – |
| Depression of gingival tissue after surgery | 1 (8.3%) | – | – |
Grade 1: Mild, no treatment or treatment with medical material or quasi-drugs was required but possible to continue the study, Grade 2: Moderate, treatment with medicine was required but possible to continue the study, Grade 3: Severe, unable to continue the study.